https://blog.wongcw.com/2022/11/25/%e6%96%b0%e7%9a%84crispr%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e7%b3%bb%e7%b5%b1%e5%8f%af%e4%bb%a5%e6%89%b9%e9%87%8f%e6%8b%96%e6%94%bedna-%e6%90%8d%e5%82%b7%e6%9b%b4%e5%b0%8f%e6%88%90/