https://blog.wongcw.com/2022/11/09/%e7%a7%91%e5%ad%b8%e5%ae%b6%e8%a8%ad%e8%a8%88crispr%e5%99%ac%e8%8f%8c%e9%ab%94-%e5%8f%af%e5%b0%8d%e7%b4%b0%e8%8f%8c%e5%af%a6%e6%96%bd%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e7%9a%84%e7%89%b9%e6%ae%8a/