https://blog.wongcw.com/2021/11/17/%e6%97%a5%e6%9c%ac%e7%a0%94%e7%a9%b6%e5%b0%8f%e7%b5%84%e5%88%a9%e7%94%a8crispr%e6%8a%80%e8%a1%93%e7%94%9f%e7%94%a2%e5%87%ba%e5%8f%af%e9%81%bf%e5%85%8d%e9%81%8e%e6%97%a9%e7%99%bc%e8%8a%bd%e7%9a%84/