https://blog.wongcw.com/2020/07/24/%e7%a7%91%e5%ad%b8%e5%ae%b6%e4%bd%bf%e7%94%a8crispr%e6%8a%80%e8%a1%93%e4%bd%bf%e5%be%97%e7%89%9b%e6%9b%b4%e6%9c%89%e5%8f%af%e8%83%bd%e7%94%a2%e7%94%9f%e9%9b%84%e6%80%a7%e5%be%8c%e4%bb%a3/