https://blog.wongcw.com/2019/10/10/%e7%a7%91%e5%ad%b8%e5%ae%b6%e4%bd%bf%e7%94%a8crispr%e6%8a%80%e8%a1%93%e6%b2%bb%e6%84%88%e5%b8%b6%e6%9c%89%e5%ae%ae%e9%a0%b8%e7%99%8c%e7%b4%b0%e8%83%9e%e7%9a%84%e5%b0%8f%e9%bc%a0/