https://blog.wongcw.com/2019/10/03/crispr%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e5%be%8c%e7%9a%84%e6%9e%9c%e8%a0%85%e8%a2%ab%e8%ad%89%e5%af%a6%e5%85%b7%e6%9c%89%e4%b8%80%e5%ae%9a%e7%9a%84%e6%8a%97%e6%af%92%e6%80%a7/