https://blog.wongcw.com/2019/05/29/%e8%8f%af%e5%a4%a7%e6%99%ba%e9%80%a0%e5%9c%a8%e7%be%8e%e5%9c%8b%e8%b5%b7%e8%a8%b4illumina-%e4%be%b5%e7%8a%af%e5%b0%88%e5%88%a9/