https://blog.wongcw.com/2019/04/17/%e5%80%9f%e5%8a%a9crispr%e6%8a%80%e8%a1%93%e7%a7%91%e5%ad%b8%e5%ae%b6%e5%90%91%e4%ba%ba%e9%ab%94%e7%b4%b0%e8%83%9e%e6%a4%8d%e5%85%a5%e9%9b%99%e6%a0%b8%e7%94%9f%e7%89%a9%e8%a8%88%e7%ae%97/