https://blog.wongcw.com/2019/03/25/dna%e8%a8%88%e7%ae%97%e6%a9%9f%e8%ad%89%e5%af%a6%e5%8c%96%e5%ad%b8%e7%b7%a8%e7%a8%8b%e6%8c%87%e6%97%a5%e5%8f%af%e5%be%85/