https://blog.wongcw.com/2018/12/28/%e5%88%a9%e7%94%a8crispr%e6%8a%80%e8%a1%93%e7%a0%b4%e8%a7%a3%e5%8f%a4%e8%80%81%e8%ac%8e%e9%a1%8c-dna%e8%a4%87%e8%a3%bd%e7%9a%84%e6%9c%80%e5%be%8c%e4%b8%80%e5%a1%8a%e6%8b%bc%e5%9c%96/